National Science Council Project Grant
Assist in establishing a screening platform
We are committed to building a comprehensive screening platform designed to accelerate the process of new drug development. This platform will integrate advanced technologies and abundant resources to provide researchers with efficient and accurate screening services. We focus on building a flexible and easy-to-use system to meet the diversity of different research needs. Through our screening platform, research teams can identify potential candidate compounds more quickly, thereby accelerating the pace of new drug development.
For users who already have screening targets but have not yet developed screening methods, we can help build a screening platform that meets customer needs. For users who already have screening platforms , we can help optimize the platform and find experimental conditions for high-throughput screening. Users must provide the necessary experimental materials for optimization.
Multiplex biological activity high-throughput screening services
A small amount of samples is enough to complete all tests!
The high-throughput screening service provided by this core facility will provide users with screening method development consultation, customized screening platform establishment, screening platform optimization, screening OEM services, and a variety of biological activity tests . The biological activity tests provided by this core facility are all tests that can be applied to high-throughput screening, requiring only a small amount of sample to complete all tests. And most tests can be completed within 3 days. In addition to the traditional biological activity tests based on visible light absorption, fluorescence intensity, and cold light intensity , this core facility can also perform biological activity tests based on fluorescent imaging , which is the so-called high-content image screening.
The biological activity tests currently provided by this core facility are:
Intracellular lipid droplet accumulation assay (LD assay)
Influenza neuraminidase inhibition assay (NA inhibition assay)
Influenza virus infection inhibition test
Antibacterial assay: Currently, we provide 3 types of antibacterial assays, including Escherichia coli, Pseudomonas aeruginosa, and Staphylococcus aureus.
Various reporter assays: NRF2 activity reporter, NF-κB activity reporter, IL-6 promoter activity reporter
Various cancer cell cytotoxicity assays